Antimicrobial prophylaxis in open lower extremity fractures

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Antimicrobial prophylaxis in open lower extremity fractures

CLINICAL QUESTION Based on the grade of open fracture, which antibiotic should be selected for antimicrobial prophylaxis, and what is the optimal timing and duration of administration? RESULTS For Grade I and II open fractures, a first-generation cephalosporin (eg, cefazolin) should be administered within 3 hours of initial injury and be continued for 24 hours after initial injury. Grade III ...

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ژورنال

عنوان ژورنال: Open Access Emergency Medicine

سال: 2011

ISSN: 1179-1500

DOI: 10.2147/oaem.s11862